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In the CRESTOR crestor clinical trial program, dipstick-positive proteinuria and microscopic hematuria were observed among CRESTOR treated patients . These findings were more frequent in patients taking CRESTOR 40 mg, when compared to lower doses of CRESTOR or comparator HMGCoA reductase inhibitors, how long for crestor to work crestor and joint pain how does crestor work to lower cholesterol side though it was generally transient and was not associated with worsening renal function . Although the clinical significance of this finding is unknown, a dose reduction should crestor be considered for patients on CRESTOR therapy with unexplained persistent proteinuria and/or hematuria during routine urinalysis testing .
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